Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.33 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.33 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30691524 | 1.00 | DPP4 (0.33) | DPP4KCNN1KCNN2KCNN3SMN1; SMN2 | |
| SCHEMBL30691382 | 0.91 | MEN1 (0.32) | L3MBTL1 | |
| SCHEMBL30691530 | 0.91 | MEN1 (0.32) | L3MBTL1 | |
| SCHEMBL30691648 | 0.91 | ADORA3 (0.36) | DPP4KCNN1KCNN2KCNN3SMN1; SMN2 | |
| SCHEMBL30691573 | 0.90 | DPP4 (0.32) | DPP4KCNN1KCNN2KCNN3SMN1; SMN2 | |
| SCHEMBL30691760 | 0.90 | DPP4 (0.32) | DPP4KCNN1KCNN2KCNN3SMN1; SMN2 | |
| SCHEMBL30691533 | 0.90 | DPP4 (0.32) | DPP4KCNN1KCNN2KCNN3SMN1; SMN2 | |
| SCHEMBL30691238 | 0.90 | DPP4 (0.32) | DPP4KCNN1KCNN2KCNN3SMN1; SMN2 | |
| SCHEMBL31570076 | 0.86 | KCNN1 (0.33) | DPP4KCNN1KCNN2KCNN3SMN1; SMN2 | |
| SCHEMBL31570049 | 0.86 | CDK1 (0.34) | KCNN1KCNN2KCNN3SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119997954-A | Compounds for the treatment of spinocerebellar ataxia type 3 | PTC医疗公司 | 2025-05-13 | — | — | CN | claimed |
| EP-4543444-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | PTC Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | claimed |
| WO-2023250316-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | PTC THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | claimed |