Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.65 |
| ▸ | AR | P10275 | 3/20 | 0.58 |
| ▸ | BTK | Q06187 | 2/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26929077 | 1.00 | CRBN (0.65) | CRBNARBTKDDB1CDK9 | |
| SCHEMBL26928997 | 0.95 | CRBN (0.60) | CRBNARBTKDDB1ALDH1A1 | |
| SCHEMBL30692979 | 0.95 | CRBN (0.60) | CRBNARBTKDDB1ALDH1A1 | |
| SCHEMBL23301420 | 0.94 | CRBN (0.72) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL27176460 | 0.91 | CRBN (0.65) | CRBNARBTKDDB1CDK9 | |
| SCHEMBL24206867 | 0.91 | CRBN (0.65) | CRBNARBTKDDB1CDK9 | |
| SCHEMBL29681788 | 0.91 | CRBN (0.65) | CRBNARBTKDDB1CDK9 | |
| SCHEMBL26969669 | 0.90 | CRBN (0.69) | CRBNARBTKDDB1CDK9 | |
| SCHEMBL31447732 | 0.89 | CRBN (0.80) | CRBNARBTKDDB1CDK9 | |
| SCHEMBL23860209 | 0.88 | CRBN (0.66) | CRBNARBTKDDB1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025228947-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF INDUCING DEGRADATION OF POLO-LIKE KINASE1 | CROSSFIRE ONCOLOGY B.V. (NL) | 2025-11-06 | — | — | WO | disclosed |
| WO-2023239629-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE CDK2 | Plexium, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |