Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185452 | 0.93 | HCAR3 (0.64) | HCAR3HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL16047037 | 0.91 | HCAR3 (0.62) | HCAR3HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29761508 | 0.85 | MAPK8 (0.55) | HCAR3HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL13015030 | 0.82 | HDAC1 (0.53) | HCAR3HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL16048668 | 0.82 | HDAC3 (0.73) | HCAR3HDAC3HDAC1HDAC2HDAC6 | |
| Hydrochloric Acid SCHEMBL3774411 | 0.81 | HDAC1 (0.52) | HCAR3HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL17832701 | 0.80 | HDAC1 (0.55) | HCAR3HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL558517 | 0.78 | CSNK2A1 (0.58) | HCAR3MAPK8MAPK9MAPK10CSNK2A1 | |
| SCHEMBL558518 | 0.78 | CSNK2A1 (0.58) | HCAR3MAPK8MAPK9MAPK10CSNK2A1 | |
| SCHEMBL14667236 | 0.77 | HDAC1 (0.57) | HCAR3HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235925-A1 | COMPOUNDS WITH MERTK ACTIVITY | MONASH UNIVERSITY (AU) | 2023-12-14 | — | — | WO | disclosed |