Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30381889 | 0.84 | TDP1 (0.47) | TDP1KDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL2418314 | 0.84 | — | — | |
| SCHEMBL14890319 | 0.81 | TDP1 (0.50) | TDP1KDM4ELMNACTSDALDH1A1 | |
| SCHEMBL868638 | 0.81 | — | — | |
| SCHEMBL8371300 | 0.81 | TDP1 (0.64) | TDP1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL13379743 | 0.81 | TDP1 (0.64) | TDP1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL30255411 | 0.81 | TDP1 (0.64) | TDP1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL8984748 | 0.81 | TDP1 (0.64) | TDP1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL4673667 | 0.79 | — | — | |
| SCHEMBL29625512 | 0.78 | KDM4E (0.36) | TDP1KDM4EKDM6BKDM5CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486875-A | Benzoquinolone-sibiricin alkaloid compound and application thereof | 山东大学 | 2024-02-02 | — | — | CN | claimed |
| CN-117486875-A | Benzoquinolone-sibiricin alkaloid compound and application thereof | 山东大学 | 2024-02-02 | — | — | CN | disclosed |