Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 5/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12513656 | 1.00 | STS (0.50) | STSPDE4BNOTCH1MAPTKDM4E | |
| SCHEMBL1968453 | 1.00 | STS (0.50) | STSPDE4BNOTCH1MAPTKDM4E | |
| SCHEMBL12513593 | 0.88 | STS (0.50) | STSPDE4BMEN1KMT2ANR1D1 | |
| SCHEMBL12435415 | 0.88 | STS (0.50) | STSPDE4BMEN1KMT2ANR1D1 | |
| SCHEMBL3999857 | 0.85 | SLC6A2 (0.47) | STSPDE4BGPR119 | |
| SCHEMBL12435403 | 0.85 | SLC6A2 (0.47) | STSPDE4BGPR119 | |
| SCHEMBL12586699 | 0.84 | MEN1 (0.47) | STSPDE4BDPP4MEN1KMT2A | |
| SCHEMBL12435411 | 0.83 | STS (0.43) | STSPDE4BMEN1KMT2AGPR119 | |
| SCHEMBL2160870 | 0.82 | RORC (0.56) | STSKDM4EGPR119 | |
| SCHEMBL19893470 | 0.82 | RORC (0.56) | STSKDM4EGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |