Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20641305 | 1.00 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL20653552 | 0.92 | ROCK2 (0.90) | ROCK2 | |
| SCHEMBL30693310 | 0.92 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL20641307 | 0.92 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL20653553 | 0.92 | ROCK2 (0.85) | ROCK2 | |
| SCHEMBL23356662 | 0.92 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL30693255 | 0.92 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL20641293 | 0.92 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL20641268 | 0.86 | ROCK2 (0.76) | ROCK2 | |
| SCHEMBL23356659 | 0.85 | ROCK2 (1.00) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869360-B | Phenylacetamides as ROCK inhibitors | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | claimed |
| CN-110869360-B | Phenylacetamides as ROCK inhibitors | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |