Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MGLL | Q99685 | 4/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15354307 | 0.82 | PTGS1 (0.55) | PTGS1PTGS2HTTSMN1; SMN2HPGD | |
| SCHEMBL19380535 | 0.82 | PTGS1 (0.60) | PTGS1PTGS2HTTSMN1; SMN2HPGD | |
| SCHEMBL17740190 | 0.81 | PTGS1 (0.63) | PTGS1PTGS2HTTSMN1; SMN2HPGD | |
| SCHEMBL12146983 | 0.81 | PTGS1 (0.63) | PTGS1PTGS2HTTSMN1; SMN2HPGD | |
| SCHEMBL9999886 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2HTTSMN1; SMN2HPGD | |
| SCHEMBL17739810 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2HTTSMN1; SMN2HPGD | |
| SCHEMBL17740192 | 0.81 | PTGS1 (0.63) | PTGS1PTGS2HTTSMN1; SMN2HPGD | |
| SCHEMBL17739715 | 0.81 | PTGS1 (0.57) | PTGS1PTGS2HTTSMN1; SMN2HPGD | |
| SCHEMBL17739717 | 0.81 | PTGS1 (0.57) | PTGS1PTGS2HTTSMN1; SMN2HPGD | |
| SCHEMBL16309303 | 0.80 | FAAH (0.46) | SMN1; SMN2FAAHRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2866849-B1 | CELL ATTACHMENT COATINGS AND METHODS USING PHOSPHOROUS-CONTAINING PHOTOREAGENT | SURMODICS INC (US) | 2020-02-19 | — | — | EP | disclosed |
| US-9631190-B2 | Cell attachment coatings and methods using phosphorous-containing photoreagent | SURMODICS, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| EP-2866849-A1 | CELL ATTACHMENT COATINGS AND METHODS USING PHOSPHOROUS-CONTAINING PHOTOREAGENT | SurModics, Inc. (US) | 2015-05-06 | — | — | EP | disclosed |
| EP-1577670-B1 | Latent reactive polymers with biologically active moieties, method of preparing a biocompatible coating and bulk material, and use | SURMODICS INC (US) | 2015-01-28 | — | — | EP | disclosed |
| EP-2148201-B1 | Latent reactive polymers with biologically active moieties | SURMODICS INC (US) | 2014-10-15 | — | — | EP | disclosed |
| WO-2014004997-A1 | CELL ATTACHMENT COATINGS AND METHODS USING PHOSPHOROUS-CONTAINING PHOTOREAGENT | SURMODICS, INC. (US) | 2014-01-03 | — | — | WO | disclosed |
| US-20140004158-A1 | CELL ATTACHMENT COATINGS AND METHODS USING PHOSPHOROUS-CONTAINING PHOTOREAGENT | BANK OF MONTREAL, AS COLLATERAL AGENT | 2014-01-02 | — | — | US | disclosed |
| US-20120171769-A1 | CELL ATTACHMENT COATINGS AND METHODS | Surmodics Coatings, LLC | 2012-07-05 | — | — | US | disclosed |
| WO-2012092566-A1 | CELL ATTACHMENT COATINGS AND METHODS | SURMODICS, INC. (US) | 2012-07-05 | — | — | WO | disclosed |
| EP-2148201-A1 | Latent reactive polymers with biologically active moieties | SurModics, Inc. (US) | 2010-01-27 | — | — | EP | disclosed |
| EP-1577670-A2 | Latent reactive polymers with biologically active moieties | SurModics, Inc. (US) | 2005-09-21 | — | — | EP | disclosed |
| EP-1003561-B1 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SURMODICS INC (US) | 2005-05-11 | — | — | EP | disclosed |
| US-20030181423-A1 | Reagent activated to form bulk material or brought into contact with surface of previously formed biomaterial and activated to form coating; pendent bioactive groups function by promoting attachment of specific molecules to surface | CLAPPER DAVID L (US) | 2003-09-25 | — | — | US | disclosed |
| US-6514734-B1 | Pendent bioactive groups function by promoting attachment of specific molecules or cells to the bulk material or coated surface; bioactive groups can include proteins, peptides, carbohydrates, and nucleic acids; e.g. neurons to electrodes | SURMODICS, INC. | 2003-02-04 | — | — | US | disclosed |
| US-6121027-A | FOR COATING BIOMATERIAL SURFACES AND FORMING A CROSSLINKED BIOMATERIAL | SURMODICS, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-1003561-A2 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SurModics, Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999008717-A2 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SURMODICS, INC. (US) | 1999-02-25 | — | — | WO | disclosed |