Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.70 |
| ▸ | CA2 | P00918 | 2/20 | 0.70 |
| ▸ | CA9 | Q16790 | 2/20 | 0.70 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.52 |
| ▸ | P4HB | P07237 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355046 | 0.95 | CA2 (0.70) | CA1CA2CA9KEAP1NFE2L2 | |
| SCHEMBL17645779 | 0.86 | CA1 (0.69) | CA1CA2CA9HDAC6HDAC3 | |
| SCHEMBL31259610 | 0.86 | HDAC2 (0.56) | CA1CA2CA9KEAP1NFE2L2 | |
| SCHEMBL2572162 | 0.84 | CA1 (0.60) | CA1CA2CA9KEAP1NFE2L2 | |
| SCHEMBL22498702 | 0.83 | CA1 (0.63) | CA1CA2CA9KEAP1NFE2L2 | |
| SCHEMBL5675802 | 0.83 | NPC1 (0.62) | CA1CA2CA9KEAP1NFE2L2 | |
| SCHEMBL17339660 | 0.82 | CA1 (0.59) | CA1CA2CA9POLBLMNA | |
| SCHEMBL26922431 | 0.82 | CA1 (0.56) | CA1CA2CA9KEAP1NFE2L2 | |
| SCHEMBL17339278 | 0.82 | CA1 (0.56) | CA1CA2CA9KEAP1NFE2L2 | |
| SCHEMBL16899331 | 0.82 | CA1 (0.71) | CA1CA2CA9HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540228-A1 | ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE | Amygdala Neurosciences, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244563-A1 | ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE | AMYGDALA NEUROSCIENCES, INC. (US) | 2023-12-21 | — | — | WO | disclosed |