Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30693786 | 1.00 | TP53 (0.66) | TP53MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30693812 | 1.00 | TP53 (0.66) | TP53MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25249238 | 0.84 | MAPT (0.57) | MAPTSMN1; SMN2TSHRLMNAITGB3 | |
| SCHEMBL30693820 | 0.83 | TP53 (0.57) | TP53MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27197306 | 0.80 | SMN1; SMN2 (0.56) | TP53MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30693840 | 0.80 | SMN1; SMN2 (0.56) | TP53MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30693817 | 0.80 | SMN1; SMN2 (0.56) | TP53MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30693907 | 0.80 | ALDH1A1 (0.49) | TP53MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27197316 | 0.80 | TP53 (0.51) | TP53MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1224023 | 0.79 | TP53 (0.71) | TP53MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274583-A2 | METHODS AND COMPOUNDS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |