SCHEMBL30693863

SCHEMBL30693863

Cn1cc(C(F)(F)F)nc1-c1ccc(CN2CC(=O)Nc3cnc(Cl)nc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27088186 1.00 USP1 (0.45) USP1
SCHEMBL30878429 0.91 USP1 (0.44) USP1
SCHEMBL29296052 0.88 USP1 (0.40) USP1
SCHEMBL27088229 0.88 USP1 (0.39) USP1
SCHEMBL30032070 0.88 USP1 (0.39) USP1
SCHEMBL29914158 0.86 USP1 (0.46) USP1
SCHEMBL30696283 0.85 USP1 (0.45) USP1
SCHEMBL27174425 0.85 USP1 (0.45) USP1
SCHEMBL30696503 0.85 USP1 (0.42) USP1
SCHEMBL30032073 0.82 USP1 (0.61) USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120092007-A Heterocyclopyrimidine compound, pharmaceutical composition and application thereof 海南先声再明医药股份有限公司 2025-06-03 — — CN disclosed
EP-4547336-A1 USP1 INHIBITORS AND USES THEREOF Zentaur Therapeutics USA Inc. (US) 2025-05-07 — — EP disclosed
CN-119836421-A USP1 inhibitors and uses thereof 森韬医药美国公司 2025-04-15 — — CN disclosed
WO-2024006879-A1 USP1 INHIBITORS AND USES THEREOF ZENTAUR THERAPEUTICS USA INC. (US) 2024-01-04 — — WO disclosed
CN-117136189-A Ubiquitin-specific protease 1 (USP 1) inhibitors 先声再明医药有限公司 2023-11-28 — — CN disclosed
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