Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31695369 | 0.87 | PTPN7 (0.54) | PTPN7STSMAOBMAOANPC1 | |
| SCHEMBL27361265 | 0.87 | PTPN7 (0.54) | PTPN7STSMAOBMAOANPC1 | |
| SCHEMBL30694638 | 0.86 | PTPN7 (0.51) | PTPN7STSMAOBMAOANPC1 | |
| SCHEMBL2110415 | 0.84 | ALDH2 (0.53) | MAOBMAOAALDH1A1GAA | |
| SCHEMBL27362897 | 0.84 | STS (0.49) | PTPN7STSMAOBMAOANPC1 | |
| SCHEMBL30694662 | 0.84 | STS (0.49) | PTPN7STSMAOBMAOANPC1 | |
| SCHEMBL3630952 | 0.82 | ALDH2 (0.51) | MAOBMAOAALDH1A1GAA | |
| SCHEMBL27361258 | 0.75 | PTPN7 (0.54) | PTPN7STSMAOBMAOANPC1 | |
| SCHEMBL2107287 | 0.74 | ALDH2 (0.53) | MAOBMAOAALDH1A1GAA | |
| SCHEMBL2110738 | 0.73 | ALDH2 (0.49) | MAOBMAOAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532016-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | University of Maryland, Baltimore (US) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |