Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30694662 | 1.00 | STS (0.49) | STSPTPN7MAOBRAB9ANPC1 | |
| SCHEMBL30694638 | 0.89 | PTPN7 (0.51) | STSPTPN7MAOBRAB9ANPC1 | |
| SCHEMBL30694672 | 0.84 | PTPN7 (0.50) | STSPTPN7MAOBRAB9ANPC1 | |
| SCHEMBL2107744 | 0.83 | ALDH2 (0.55) | MAOBRAB9ANPC1MAOAPOLB | |
| SCHEMBL2107421 | 0.73 | ALDH2 (0.68) | MAOBMAOA | |
| SCHEMBL2109160 | 0.72 | ALDH2 (0.48) | MAOBRAB9ANPC1MAOAPOLB | |
| SCHEMBL3419330 | 0.72 | ALDH2 (0.59) | MAOBRAB9ANPC1MAOAPOLB | |
| SCHEMBL2108736 | 0.72 | ALDH2 (0.58) | MAOBMAOAMAPT | |
| SCHEMBL18153391 | 0.71 | STS (0.64) | STSMAOBRAB9ANPC1MAOA | |
| SCHEMBL2110402 | 0.70 | MAPT (0.64) | MAOBRAB9ANPC1MAOAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |