SCHEMBL30695000

SCHEMBL30695000

O=C(Nc1nn(Cc2ccc(C(F)(F)F)cc2)c2ccccc12)c1ccsc1Cl

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FSCN1 Q16658 1/20 0.66
PTGER4 P35408 9/20 0.51
CPT1A P50416 1/20 0.47
NR3C1 P04150 6/20 0.41
ADORA3 P0DMS8 1/20 0.41
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
NCOR2 Q9Y618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17038823 1.00 FSCN1 (0.66) FSCN1PTGER4CPT1ANR3C1ADORA3
SCHEMBL17199348 0.89 FSCN1 (0.51) FSCN1PTGER4CPT1AHDAC3HDAC1
SCHEMBL21662154 0.88 FSCN1 (0.53) FSCN1PTGER4CPT1ANR3C1ADORA3
SCHEMBL17038824 0.86 FSCN1 (0.66) FSCN1PTGER4CPT1AADORA3HDAC3
SCHEMBL30695006 0.86 FSCN1 (0.66) FSCN1PTGER4CPT1AADORA3HDAC3
SCHEMBL30501125 0.86 FSCN1 (0.70) FSCN1PTGER4CPT1ANR3C1ADORA3
SCHEMBL17038973 0.86 FSCN1 (0.70) FSCN1PTGER4CPT1ANR3C1ADORA3
SCHEMBL17038827 0.85 FSCN1 (0.69) FSCN1PTGER4CPT1AADORA3
SCHEMBL30501120 0.85 FSCN1 (0.69) FSCN1PTGER4CPT1AADORA3
SCHEMBL30695042 0.85 FSCN1 (0.66) FSCN1PTGER4CPT1AADORA3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333411-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN CORNELL UNIVERSITY (US) 2025-10-30 US disclosed
US-12168658-B2 Compounds and methods for inhibiting fascin NOVITA PHARMACEUTICALS, INC. (US) 2024-12-17 US disclosed
US-20240124449-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN NOVITA PHARMACEUTICALS, INC. (US) 2024-04-18 US disclosed
US-11858929-B2 Compounds and methods for inhibiting fascin CORNELL UNIVERSITY (US) 2024-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124449-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN FSCN1, MTPN, MYOF FSCN1 1/4885PTGER4 4107/4885CPT1A 117/4885
US-20250333411-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN FSCN1, MTPN, MYOF FSCN1 1/4885PTGER4 4107/4885CPT1A 117/4885
US-11858929-B2 Compounds and methods for inhibiting fascin FSCN1, MTPN, MYOF FSCN1 1/4885PTGER4 4107/4885CPT1A 117/4885
US-12168658-B2 Compounds and methods for inhibiting fascin FSCN1, MTPN, MYOF FSCN1 1/4885PTGER4 4107/4885CPT1A 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.