Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.36 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27356799 | 0.89 | CRBN (0.37) | CRBNDDB1GSPT1STAT3KDM4E | |
| SCHEMBL30696727 | 0.82 | KDM4E (0.41) | KDM4EMAPT | |
| SCHEMBL27354582 | 0.80 | CRBN (0.43) | CRBNDDB1GSPT1STAT3 | |
| SCHEMBL30696780 | 0.77 | KDM4E (0.40) | KDM4EMAPT | |
| SCHEMBL22297613 | 0.75 | CRBN (0.56) | CRBNDDB1GSPT1 | |
| SCHEMBL27356789 | 0.74 | BCHE (0.41) | KDM4E | |
| SCHEMBL31457822 | 0.72 | LRRK2 (0.48) | CRBNDDB1STAT3MAPT | |
| SCHEMBL27356805 | 0.69 | CRBN (0.43) | CRBNDDB1GSPT1STAT3 | |
| SCHEMBL30696605 | 0.69 | CRBN (0.53) | CRBNDDB1GSPT1STAT3MAPT | |
| SCHEMBL31476885 | 0.69 | CD274 (0.39) | CRBNDDB1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543439-A2 | NRF2 PROTEIN DEGRADERS | Ganymede Oncology, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006742-A2 | NRF2 PROTEIN DEGRADERS | DRACEN PHARMACEUTICALS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |