SCHEMBL30696906

SCHEMBL30696906

CN1CC(=O)Nc2cccc(Br)c21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
CRBN Q96SW2 1/20 0.42
BRD4 O60885 4/20 0.41
CREBBP Q92793 3/20 0.41
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
HTR1A P08908 3/20 0.38
CCNB2 O95067 1/20 0.36
CDK1 P06493 1/20 0.36
CCNB1 P14635 1/20 0.36
GSK3B P49841 1/20 0.36
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
CCNB3 Q8WWL7 1/20 0.36
EPHX2 P34913 1/20 0.36
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26677680 1.00 KMT2A (0.48) KMT2AMEN1CRBNBRD4CREBBP
SCHEMBL31170855 0.81 CRBN (0.44) KMT2AMEN1CRBNBRD4CREBBP
SCHEMBL9715259 0.81 KMT2A (0.52) KMT2AMEN1CRBNBRD4CREBBP
SCHEMBL26677608 0.80 MEN1 (0.34) KMT2AMEN1BRD4CREBBPALDH1A1
SCHEMBL13150917 0.80 CRBN (0.42) KMT2AMEN1CRBNBRD4CREBBP
SCHEMBL30697067 0.80 MEN1 (0.34) KMT2AMEN1BRD4CREBBPALDH1A1
SCHEMBL3593117 0.80 CRBN (0.42) KMT2AMEN1CRBNBRD4CREBBP
SCHEMBL3593120 0.80 CRBN (0.42) KMT2AMEN1CRBNBRD4CREBBP
SCHEMBL13382909 0.78 CRBN (0.40) KMT2AMEN1CRBNBRD4CREBBP
SCHEMBL1549056 0.76 MEN1 (0.52) KMT2AMEN1CRBNBRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4539849-A1 COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 C4 Therapeutics, Inc. (US) 2025-04-23 EP disclosed
EP-4532485-A1 TYK2 INHIBITORS AND USES THEREOF Sudo Biosciences Limited (GB) 2025-04-09 EP disclosed
WO-2023244764-A1 COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 C4 THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed
WO-2023227946-A1 TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LIMITED (GB) 2023-11-30 WO disclosed