Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | SCD | O00767 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TAS2R8 | Q9NYW2 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30697101 | 0.78 | HDAC3 (0.47) | HDAC3HDAC8NCOR2SCDALDH1A1 | |
| SCHEMBL29276689 | 0.77 | HDAC3 (0.59) | HDAC3HDAC8NCOR2SCDALDH1A1 | |
| SCHEMBL30660584 | 0.77 | HDAC3 (0.59) | HDAC3HDAC8NCOR2SCDALDH1A1 | |
| SCHEMBL31691471 | 0.77 | HDAC3 (0.49) | HDAC3HDAC8NCOR2SCDHPGD | |
| SCHEMBL30697035 | 0.75 | PTGER1 (0.56) | — | |
| SCHEMBL30660594 | 0.74 | HDAC3 (0.60) | HDAC3HDAC8NCOR2SCDALDH1A1 | |
| SCHEMBL23177724 | 0.73 | CA1 (0.47) | KDM4E | |
| SCHEMBL31691482 | 0.73 | SCD (0.50) | HDAC3HDAC8NCOR2SCDTAS2R8 | |
| SCHEMBL4345991 | 0.72 | METAP1 (0.62) | ALDH1A1RAB9AKDM4ENAMPTMETAP1 | |
| SCHEMBL25225604 | 0.72 | SCD (0.44) | HDAC3HDAC8NCOR2SCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451961-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 广州科恩泰生物医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-117186098-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 上海科恩泰生物医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |