Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 19/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17694781 | 0.83 | PTGER1 (0.57) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL30697146 | 0.79 | MPO (0.46) | PTGER1CYP1A2CYP2C19NPC1 | |
| SCHEMBL29276691 | 0.77 | PTGER1 (0.52) | PTGER1CYP2C9CYP1A2CYP2C19NPC1 | |
| SCHEMBL30697074 | 0.76 | MEN1 (0.58) | CYP1A2CYP2C19 | |
| SCHEMBL30697025 | 0.75 | HDAC3 (0.50) | — | |
| SCHEMBL14097081 | 0.74 | PTGER1 (0.54) | PTGER1CYP2C9CYP1A2CYP2C19NPC1 | |
| SCHEMBL26931352 | 0.73 | PTGER1 (0.53) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL30660590 | 0.73 | PTGER1 (0.53) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL13693161 | 0.72 | PTGER1 (0.81) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL13693152 | 0.72 | PTGER1 (1.00) | PTGER1CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451961-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 广州科恩泰生物医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-117186098-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 上海科恩泰生物医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |