Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18325651 | 0.83 | RIPK1 (0.48) | RIPK1MEN1KMT2AATMSSTR4 | |
| SCHEMBL12454614 | 0.82 | RIPK1 (0.46) | RIPK1MEN1KMT2AATMHTR2C | |
| SCHEMBL25839004 | 0.82 | EED (0.41) | RIPK1MEN1KMT2ASSTR4HTR2C | |
| SCHEMBL26677600 | 0.81 | KDM4E (0.51) | RIPK1MEN1KMT2AATMKDM4E | |
| SCHEMBL8017533 | 0.80 | HTR2C (0.47) | RIPK1MEN1KMT2AATMHTR2C | |
| SCHEMBL15261724 | 0.80 | NPC1 (0.41) | RIPK1HTR2CSLC6A4ALDH1A1CACNA1G | |
| SCHEMBL15261600 | 0.80 | HTR2C (0.43) | RIPK1MEN1KMT2ASSTR4HTR2C | |
| SCHEMBL24643275 | 0.80 | SSTR4 (0.38) | RIPK1MEN1KMT2AATMSSTR4 | |
| SCHEMBL12068165 | 0.80 | RIPK1 (0.47) | RIPK1SSTR4HTR2CSLC6A4HTR2A | |
| SCHEMBL31137753 | 0.80 | RIPK1 (0.47) | RIPK1SSTR4HTR2CSLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532485-A1 | TYK2 INHIBITORS AND USES THEREOF | Sudo Biosciences Limited (GB) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023227946-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2023-11-30 | — | — | WO | disclosed |