Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 12/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22711487 | 1.00 | SYK (0.49) | SYKABCB1HTR1ADRD2GCK | |
| SCHEMBL30697237 | 1.00 | SYK (0.49) | SYKABCB1HTR1ADRD2GCK | |
| SCHEMBL25319633 | 0.80 | RAB9A (0.56) | SYKABCB1HTR1ADRD2AURKB | |
| SCHEMBL22711485 | 0.77 | SYK (0.46) | SYKABCB1HTR1ADRD2GCK | |
| SCHEMBL22711439 | 0.76 | TDP1 (0.47) | HTR1ADRD2GCKALDH1A1SMN1; SMN2 | |
| SCHEMBL21801177 | 0.75 | SYK (0.65) | SYKABCB1HTR1ADRD2AURKB | |
| SCHEMBL29114713 | 0.75 | SYK (0.52) | SYKAURKBINCENPKDM4EALDH1A1 | |
| SCHEMBL22711449 | 0.73 | SMN1; SMN2 (0.43) | ABCB1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL23039642 | 0.73 | SYK (0.42) | SYKABCB1HTR1ADRD2GCK | |
| SCHEMBL30696982 | 0.73 | SYK (0.42) | SYKABCB1HTR1ADRD2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655685-B | Thiophene derivative and use thereof | 藤本株式会社 | 2023-11-17 | — | — | CN | disclosed |