Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27526139 | 0.73 | PPARG (0.41) | KDM4EALDH1A1SMN1; SMN2PPARGMDM2 | |
| SCHEMBL30292355 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2PPARGMDM2 | |
| SCHEMBL23890365 | 0.72 | KDM4E (0.64) | KDM4EALDH1A1SMN1; SMN2FABP4PARP1 | |
| SCHEMBL29114286 | 0.72 | PLA2G1B (0.52) | KDM4EALDH1A1SMN1; SMN2PPARGFABP4 | |
| SCHEMBL27526405 | 0.70 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL8575121 | 0.69 | GUCY1A1 (0.50) | CNR2DRD4TLR7 | |
| SCHEMBL27525861 | 0.67 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2PPARGFABP4 | |
| SCHEMBL2358405 | 0.67 | PLK1 (0.51) | KDM4EALDH1A1CNR2PLK1 | |
| SCHEMBL23141314 | 0.67 | PLK1 (0.46) | KDM4EALDH1A1PPARGCNR2PLK1 | |
| SCHEMBL8575119 | 0.67 | GUCY1A1 (0.49) | CNR2DRD4TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110891935-B | Bicyclic compounds and their use in cancer treatment | 泰普斯特医疗公司 | 2023-12-01 | — | — | CN | disclosed |