Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.50 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575119 | 0.90 | GUCY1A1 (0.49) | GUCY1A1GUCY1B1CNR2CNR1DRD4 | |
| SCHEMBL8452734 | 0.86 | GUCY1A1 (0.52) | GUCY1A1GUCY1B1CNR2CNR1SLC6A3 | |
| SCHEMBL8452079 | 0.84 | GUCY1A1 (0.57) | GUCY1A1GUCY1B1CNR2CNR1SLC6A3 | |
| SCHEMBL8448653 | 0.81 | CNR2 (0.60) | GUCY1A1GUCY1B1CNR2CNR1SLC6A3 | |
| SCHEMBL8452729 | 0.76 | GUCY1A1 (0.52) | GUCY1A1GUCY1B1CNR2CNR1TLR7 | |
| SCHEMBL8452077 | 0.75 | GUCY1A1 (0.55) | GUCY1A1GUCY1B1CNR2CNR1SLC6A3 | |
| SCHEMBL8448651 | 0.72 | GUCY1A1 (0.57) | GUCY1A1GUCY1B1CNR2CNR1SLC6A3 | |
| SCHEMBL3897756 | 0.70 | GUCY1A1 (0.94) | GUCY1A1GUCY1B1CNR2CNR1SLC6A3 | |
| SCHEMBL30697462 | 0.69 | KDM4E (0.45) | CNR2DRD4TLR7 | |
| SCHEMBL29988457 | 0.64 | CNR2 (1.00) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856326-A | ANTITUMOR, ANTICANCER AGENTS | MERCK & CO., INC. (US) | 1999-01-05 | — | — | US | disclosed |