Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635917 | 1.00 | STING1 (0.55) | STING1KDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23635919 | 0.92 | STING1 (0.57) | STING1KDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL30697667 | 0.92 | STING1 (0.57) | STING1KDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23630785 | 0.90 | STING1 (0.62) | STING1KDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23630807 | 0.89 | STING1 (0.69) | STING1MAPK1HTTMCL1 | |
| SCHEMBL23112009 | 0.88 | STING1 (0.60) | STING1KDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL30697670 | 0.87 | STING1 (0.53) | STING1KDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23635920 | 0.87 | STING1 (0.53) | STING1KDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23635875 | 0.85 | ALDH1A1 (0.59) | STING1KDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL30697675 | 0.85 | ALDH1A1 (0.59) | STING1KDM4EALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793988-B1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-11-15 | — | — | EP | disclosed |