Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30698086 | 1.00 | PSENEN (0.52) | PSENENKLK5CTSSCTSKPSEN1 | |
| SCHEMBL30698097 | 1.00 | PSENEN (0.52) | PSENENKLK5CTSSCTSKPSEN1 | |
| SCHEMBL30698109 | 1.00 | PSENEN (0.52) | PSENENKLK5CTSSCTSKPSEN1 | |
| SCHEMBL30406679 | 0.92 | CTSK (0.50) | PSENENKLK5CTSSCTSKPSEN1 | |
| SCHEMBL30064700 | 0.92 | CTSK (0.50) | PSENENKLK5CTSSCTSKPSEN1 | |
| SCHEMBL29918096 | 0.90 | CTSK (0.49) | PSENENKLK5CTSSCTSKPSEN1 | |
| SCHEMBL2413839 | 0.89 | PSENEN (0.46) | PSENENKLK5CTSSCTSKPSEN1 | |
| SCHEMBL2413834 | 0.89 | PSENEN (0.46) | PSENENKLK5CTSSCTSKPSEN1 | |
| SCHEMBL17137934 | 0.89 | PSENEN (0.59) | PSENENKLK5CTSSCTSKPSEN1 | |
| SCHEMBL7104010 | 0.89 | PSENEN (0.59) | PSENENKLK5CTSSCTSKPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831391-B | Dipeptide compound capable of exerting rapid antidepressant effect and application thereof | 南京医科大学 | 2023-10-13 | — | — | CN | disclosed |