Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 9/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699964 | 0.85 | SCN9A (0.40) | SCN9ASCN7AKCNH2LIPEBCHE | |
| SCHEMBL27291672 | 0.85 | SCN9A (0.40) | SCN9ASCN7AKCNH2LIPEBCHE | |
| SCHEMBL30700461 | 0.84 | BTK (0.40) | SCN9AFPR1FPR2HCRTR1IDO1 | |
| SCHEMBL30700101 | 0.84 | BTK (0.40) | SCN9AFPR1FPR2HCRTR1IDO1 | |
| SCHEMBL30700128 | 0.82 | PARP10 (0.44) | KCNH2HRH3 | |
| SCHEMBL30700532 | 0.82 | PARP10 (0.44) | KCNH2HRH3 | |
| SCHEMBL27291568 | 0.82 | PARP10 (0.44) | KCNH2HRH3 | |
| SCHEMBL30700300 | 0.81 | SCN9A (0.44) | SCN9ASCN7AKCNH2LIPEBCHE | |
| SCHEMBL30700013 | 0.80 | HRH3 (0.40) | KCNH2HRH3 | |
| SCHEMBL30700222 | 0.77 | SCN9A (0.42) | SCN9ASCN7AKCNH2LIPEFPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |