2-Mercaptonicotinic Acid

2-Mercaptonicotinic Acid

SCHEMBL3070055

CS.O=C(O)c1cccnc1S

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.59
TDP1 Q9NUW8 1/20 0.59
ALDH1A1 P00352 8/20 0.57
MAPT P10636 2/20 0.57
ALOX15 P16050 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
NPSR1 Q6W5P4 2/20 0.57
CYP3A4 P08684 1/20 0.57
TSHR P16473 1/20 0.57
BLM P54132 1/20 0.57
AGER Q15109 1/20 0.57
LMNA P02545 3/20 0.55
NAPRT Q6XQN6 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
MYC P01106 1/20 0.50
DHODH Q02127 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
GAA P10253 2/20 0.45
KMT2A Q03164 1/20 0.44
ALOX12 P18054 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptonicotinic Acid SCHEMBL261186 0.96 KDM4E (0.63) KDM4ETDP1ALDH1A1MAPTALOX15
2-Mercaptonicotinic Acid SCHEMBL29382089 0.96 KDM4E (0.63) KDM4ETDP1ALDH1A1MAPTALOX15
2-Mercaptonicotinic Acid SCHEMBL29181672 0.94 KDM4E (0.61) KDM4ETDP1ALDH1A1MAPTALOX15
2-Mercaptonicotinic Acid SCHEMBL30605292 0.94 KDM4E (0.61) KDM4ETDP1ALDH1A1MAPTALOX15
2-Mercaptonicotinic Acid SCHEMBL29105774 0.94 KDM4E (0.61) KDM4ETDP1ALDH1A1MAPTALOX15
2-Mercaptonicotinic Acid SCHEMBL28567701 0.89 KDM4E (0.55) KDM4ETDP1ALDH1A1MAPTALOX15
2-Mercaptonicotinic Acid SCHEMBL9065450 0.87 NAPRT (0.55) KDM4ETDP1ALDH1A1MAPTALOX15
2-Mercaptonicotinic Acid SCHEMBL5741948 0.85 KDM4E (0.52) KDM4ETDP1ALDH1A1MAPTALOX15
SCHEMBL27951997 0.82 KDM4E (0.45) KDM4ETDP1ALDH1A1MAPTALOX15
2-Mercaptonicotinic Acid SCHEMBL1840781 0.81 KDM4E (0.44) KDM4ETDP1ALDH1A1MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20090163628-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT STURGILL JEFFREY ALLEN 2009-06-25 US disclosed
US-7422793-B2 Non-toxic corrosion-protection rinses and seals based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-09-09 US disclosed
US-7407711-B2 Non-toxic corrosion-protection conversion coats based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-08-05 US disclosed
US-7294211-B2 Non-toxic corrosion-protection conversion coats based on cobalt UNIVERSITY OF DAYTON (US) 2007-11-13 US disclosed
US-7291217-B2 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON (US) 2007-11-06 US disclosed
US-20070149673-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE STURGILL JEFFREY A 2007-06-28 US disclosed
US-7235142-B2 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON (US) 2007-06-26 US disclosed
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 EP disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 US disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed