Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPC | P11150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700026 | 0.84 | MGLL (0.44) | MGLLLIPGIDO1ENPP2ATXN2 | |
| SCHEMBL30700507 | 0.83 | MGLL (0.44) | MGLLLIPGIDO1ENPP2ATXN2 | |
| SCHEMBL30700153 | 0.83 | MGLL (0.44) | MGLLLIPGIDO1ENPP2ATXN2 | |
| SCHEMBL30700090 | 0.80 | MGLL (0.41) | MGLLLIPGIDO1ENPP2ATXN2 | |
| SCHEMBL27290142 | 0.80 | MGLL (0.41) | MGLLLIPGIDO1ENPP2ATXN2 | |
| SCHEMBL30699955 | 0.79 | MGLL (0.41) | MGLLLIPGENPP2ATXN2LPL | |
| SCHEMBL30699984 | 0.79 | MGLL (0.41) | MGLLLIPGUSP2PKMENPP2 | |
| SCHEMBL30700493 | 0.79 | MGLL (0.41) | MGLLLIPGPKMENPP2ATXN2 | |
| SCHEMBL27292384 | 0.79 | MGLL (0.41) | MGLLLIPGENPP2ATXN2LPL | |
| SCHEMBL30700801 | 0.79 | MGLL (0.47) | MGLLLIPGIDO1ENPP2ATXN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |