Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31308764 | 1.00 | GPR119 (0.50) | GPR119DGAT1P2RX3P2RX2ACACB | |
| SCHEMBL25298984 | 0.83 | GPR119 (0.48) | GPR119DGAT1LOXL2 | |
| SCHEMBL30395753 | 0.83 | GPR119 (0.48) | GPR119DGAT1LOXL2 | |
| SCHEMBL30409514 | 0.81 | IDH1 (0.45) | GPR119 | |
| SCHEMBL30409940 | 0.81 | IDH1 (0.45) | GPR119 | |
| SCHEMBL30700772 | 0.81 | EIF2AK4 (0.41) | GPR119DGAT1P2RX3P2RX2ACACB | |
| SCHEMBL30409580 | 0.80 | GPR119 (0.39) | GPR119ACACB | |
| SCHEMBL25260355 | 0.80 | GPR119 (0.41) | GPR119P2RX3P2RX2ACACB | |
| SCHEMBL31308005 | 0.79 | HCRTR1 (0.37) | GPR119 | |
| SCHEMBL29426989 | 0.78 | GPR119 (0.44) | GPR119DGAT1ACACBABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |