Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | MST1R | Q04912 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700995 | 0.80 | CDC7 (0.50) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL18789132 | 0.75 | PRKCI (0.56) | CLK4PIM1ROCK1DYRK1BPRKCI | |
| SCHEMBL30543363 | 0.71 | GSTP1 (0.43) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL30311795 | 0.70 | BRAF (0.35) | IDO1BRAFATRATRIP | |
| SCHEMBL14352065 | 0.70 | CDC7 (0.46) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL30775203 | 0.70 | PARP10 (0.45) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL29736680 | 0.69 | MAP4K1 (0.50) | — | |
| SCHEMBL24466337 | 0.68 | CDK5 (0.46) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL15566157 | 0.68 | CLK4 (0.46) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL16921409 | 0.68 | CDK5 (0.46) | CDK5DYRK1ACLK4PIM1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295737-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-12-26 | — | — | CN | disclosed |