Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 6/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19778605 | 0.86 | KDM4E (0.49) | L3MBTL1KDM4EALDH1A1SMN1; SMN2ABL1 | |
| SCHEMBL31267853 | 0.80 | L3MBTL1 (0.41) | L3MBTL1KDM4EALDH1A1SMN1; SMN2ABL1 | |
| SCHEMBL26040458 | 0.78 | NQO2 (0.46) | L3MBTL1KDM4EALDH1A1ABL1NQO2 | |
| SCHEMBL23090012 | 0.75 | HPGD (0.41) | ALDH1A1SMN1; SMN2ABL1NR4A2GAA | |
| SCHEMBL31160530 | 0.75 | HPGD (0.41) | ALDH1A1SMN1; SMN2ABL1NR4A2GAA | |
| SCHEMBL31636694 | 0.75 | ABL1 (0.41) | ALDH1A1SMN1; SMN2ABL1NR4A2GAA | |
| SCHEMBL23066024 | 0.75 | ABL1 (0.41) | ALDH1A1SMN1; SMN2ABL1NR4A2GAA | |
| SCHEMBL15351124 | 0.74 | ATR (0.50) | L3MBTL1KDM4EALDH1A1SMN1; SMN2ABL1 | |
| SCHEMBL29593855 | 0.74 | ATR (0.50) | L3MBTL1KDM4EALDH1A1SMN1; SMN2ABL1 | |
| SCHEMBL22717309 | 0.72 | SMN1; SMN2 (0.45) | L3MBTL1KDM4EALDH1A1SMN1; SMN2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724441-A1 | ISOINDOLINONE AND DIHYDROPYRROLOPRIDINONE COMPOUNDS AND USES THEREOF | Revir Therapeutics, Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024251212-A1 | ISOINDOLINONE AND DIHYDROPYRROLOPRIDINONE COMPOUNDS AND USES THEREOF | REVIR THERAPEUTICS, INC. (US) | 2024-12-12 | — | — | WO | disclosed |
| WO-2024251211-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR MODULATING SPLICING OF MSH3 | REVIR THERAPEUTICS, INC. (US) | 2024-12-12 | — | — | WO | disclosed |
| CN-117295737-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-12-26 | — | — | CN | disclosed |