Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 4/20 | 0.55 |
| ▸ | WNT3A | P56704 | 4/20 | 0.55 |
| ▸ | THRA | P10827 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12391580 | 1.00 | CTNNB1 (0.55) | CTNNB1WNT3ATHRATHRBKMT2A | |
| SCHEMBL9509517 | 0.89 | THRA (0.60) | THRATHRBKMT2AGSREGFR | |
| SCHEMBL29062364 | 0.85 | CTNNB1 (0.70) | CTNNB1WNT3AKMT2AHPGDTDP1 | |
| SCHEMBL30089541 | 0.85 | CTNNB1 (0.70) | CTNNB1WNT3AKMT2AHPGDTDP1 | |
| SCHEMBL27256141 | 0.83 | GSR (0.51) | THRATHRBKMT2AGSREGFR | |
| SCHEMBL11271365 | 0.83 | THRA (0.55) | CTNNB1THRATHRBKMT2APARP1 | |
| SCHEMBL30317739 | 0.83 | THRA (0.55) | CTNNB1THRATHRBKMT2APARP1 | |
| SCHEMBL14431581 | 0.82 | HPGD (0.59) | CTNNB1WNT3AKMT2AHPGDTDP1 | |
| SCHEMBL116221 | 0.81 | THRA (0.53) | CTNNB1WNT3ATHRATHRBKMT2A | |
| SCHEMBL5954219 | 0.81 | THRA (0.53) | THRATHRBKMT2AHPGDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069514-B | Antibacterial compound and application thereof | 结核病药物开发全球联盟公司 | 2023-12-29 | — | — | CN | disclosed |