Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.73 |
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29111785 | 0.94 | NPC1 (0.65) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11763796 | 0.94 | NPC1 (0.65) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11763637 | 0.94 | NPC1 (0.68) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29111788 | 0.91 | NPC1 (0.61) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL15333724 | 0.85 | NPC1 (0.60) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14821507 | 0.85 | NPC1 (0.59) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9585904 | 0.84 | LMNA (0.54) | NPC1RAB9ALMNAALDH1A1GABRA2 | |
| SCHEMBL168643 | 0.84 | NPC1 (1.00) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11765664 | 0.84 | NPC1 (0.67) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14813033 | 0.83 | NPC1 (0.74) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088861-A | 2-substituted aryl-oxazolin-4-one derivative and application thereof | 浙江大学 | 2023-11-21 | — | — | CN | disclosed |