SCHEMBL30701196

SCHEMBL30701196

COc1cnc(OC)c(CO)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.41
CYP11B2 P19099 2/20 0.41
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
DPP4 P27487 1/20 0.37
HTT P42858 1/20 0.36
MAPT P10636 1/20 0.35
CASP1 P29466 1/20 0.35
F2 P00734 1/20 0.35
GLA P06280 1/20 0.35
HPGD P15428 1/20 0.35
MTNR1B P49286 4/20 0.35
MTNR1A P48039 3/20 0.35
SLC13A5 Q86YT5 2/20 0.35
SLC13A2 Q13183 1/20 0.35
SLC13A3 Q8WWT9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19330145 1.00 CYP11B1 (0.41) CYP11B1CYP11B2PDE4APDE4BPDE4C
SCHEMBL19330175 0.84 ACACB (0.38) CYP11B1CYP11B2PDE4APDE4BPDE4C
SCHEMBL28483675 0.82 DPP4 (0.45) CYP11B1CYP11B2PDE4APDE4BPDE4C
SCHEMBL5780868 0.81 SLC13A5 (0.50) CYP11B1CYP11B2PDE4APDE4BPDE4C
SCHEMBL19330286 0.81 MAPT (0.35) ALDH1A1MAPTCASP1F2GLA
SCHEMBL31032826 0.81 ALDH1A1 (0.43) CYP11B1CYP11B2PDE4APDE4BPDE4C
SCHEMBL31032811 0.81 PDE4A (0.38) CYP11B1CYP11B2PDE4APDE4BPDE4C
SCHEMBL5783160 0.79 CYP2C9 (0.42) CYP11B1CYP11B2PDE4APDE4BPDE4C
SCHEMBL20565731 0.79 ALDH1A1 (0.51) CYP11B1CYP11B2PDE4APDE4BPDE4C
SCHEMBL5783206 0.79 PDE4A (0.37) CYP11B1CYP11B2PDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109069514-B Antibacterial compound and application thereof 结核病药物开发全球联盟公司 2023-12-29 CN disclosed