Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24683195 | 1.00 | MAOB (0.38) | MAOBMAPTTP53LMNAMAPK1 | |
| SCHEMBL24682969 | 0.90 | MAOB (0.39) | MAOBMAPTLMNAMAPK1ESR1 | |
| SCHEMBL30701683 | 0.90 | MAOB (0.39) | MAOBMAPTLMNAMAPK1ESR1 | |
| SCHEMBL29800050 | 0.86 | MAPT (0.42) | MAOBMAPTLMNAMAPK1ESR1 | |
| SCHEMBL24683885 | 0.86 | MAPT (0.42) | MAOBMAPTLMNAMAPK1ESR1 | |
| SCHEMBL24683213 | 0.81 | MAOB (0.40) | MAOBMAPTLMNAMAPK1ESR1 | |
| SCHEMBL29799904 | 0.81 | MAOB (0.40) | MAOBMAPTLMNAMAPK1ESR1 | |
| SCHEMBL24683224 | 0.81 | HSP90AA1 (0.39) | LMNAHSP90AA1HSP90B1TAAR1PKM | |
| SCHEMBL30664668 | 0.81 | HSP90AA1 (0.39) | LMNAHSP90AA1HSP90B1TAAR1PKM | |
| SCHEMBL24683894 | 0.81 | MAOB (0.39) | MAOBMAPTMAPK1ESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |