Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30664668 | 1.00 | HSP90AA1 (0.39) | HSP90AA1HSP90B1LMNAHTTSMN1; SMN2 | |
| SCHEMBL24683191 | 0.91 | HSP90AA1 (0.38) | HSP90AA1HSP90B1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30664665 | 0.91 | HSP90AA1 (0.38) | HSP90AA1HSP90B1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29800145 | 0.87 | TAAR1 (0.36) | HSP90AA1HSP90B1LMNAHTTTDP1 | |
| SCHEMBL24683891 | 0.87 | TAAR1 (0.36) | HSP90AA1HSP90B1LMNAHTTTDP1 | |
| SCHEMBL24683888 | 0.87 | HSP90AA1 (0.40) | HSP90AA1HSP90B1LMNAPKMALDH1A1 | |
| SCHEMBL30701679 | 0.87 | HSP90AA1 (0.40) | HSP90AA1HSP90B1LMNAPKMALDH1A1 | |
| SCHEMBL29800061 | 0.85 | TAAR1 (0.36) | SMN1; SMN2TAAR1ALDH1A1NPC1RAB9A | |
| SCHEMBL24683205 | 0.83 | LMNA (0.38) | HSP90AA1HSP90B1LMNASMN1; SMN2TDP1 | |
| SCHEMBL29799927 | 0.83 | LMNA (0.38) | HSP90AA1HSP90B1LMNASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |