Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | HTR2C | P28335 | 6/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 4/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31599823 | 0.84 | HTR2A (0.44) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL29241352 | 0.78 | HTR2A (0.40) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL18366276 | 0.77 | CYP17A1 (0.34) | HTR2AHTR2CKMONT5E | |
| SCHEMBL24147792 | 0.77 | KMO (0.55) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL29241346 | 0.76 | KMO (0.43) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL31394462 | 0.74 | HTR2A (0.52) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL29080920 | 0.72 | — | — | |
| SCHEMBL31716783 | 0.72 | HTR2A (0.47) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL24338626 | 0.72 | HTR2A (0.39) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL30174435 | 0.72 | HTR2A (0.39) | HTR2AHTR2CHTR2BHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547657-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119384415-A | CD73 compounds | 吉利德科学公司 | 2025-01-28 | — | — | CN | disclosed |
| WO-2024006929-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-01-04 | — | — | WO | disclosed |