Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 11/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191366 | 1.00 | QPCT (0.41) | QPCTQPCTLCYP1A2METAP2MDM2 | |
| SCHEMBL27191340 | 0.79 | QPCT (0.41) | QPCTQPCTLCYP1A2METAP2MDM2 | |
| SCHEMBL27191308 | 0.77 | QPCT (0.41) | QPCTQPCTLCYP1A2METAP2MDM2 | |
| SCHEMBL30947432 | 0.76 | QPCT (0.43) | QPCTQPCTLCYP1A2METAP2MDM2 | |
| SCHEMBL30701743 | 0.76 | QPCT (0.43) | QPCTQPCTLCYP1A2METAP2MDM2 | |
| SCHEMBL29565225 | 0.75 | QPCT (0.40) | QPCTQPCTLCYP1A2METAP2MDM2 | |
| SCHEMBL22869317 | 0.75 | QPCT (0.40) | QPCTQPCTLCYP1A2METAP2MDM2 | |
| SCHEMBL24408623 | 0.75 | QPCT (0.42) | QPCTQPCTLCYP1A2METAP2MDM2 | |
| SCHEMBL30701653 | 0.73 | QPCT (0.44) | QPCTQPCTLCYP1A2METAP2MDM2 | |
| SCHEMBL22869325 | 0.73 | QPCT (0.44) | QPCTQPCTLCYP1A2METAP2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547657-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119384415-A | CD73 compounds | 吉利德科学公司 | 2025-01-28 | — | — | CN | disclosed |
| WO-2024006929-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-01-04 | — | — | WO | disclosed |