Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.35 |
| ▸ | DPYD | Q12882 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559799 | 0.76 | ALDH1A1 (0.49) | ALDH1A1ATAD2NT5ELMNA | |
| Hydrochloric Acid SCHEMBL3558331 | 0.75 | ALDH1A1 (0.47) | ALDH1A1ATAD2NT5ELMNA | |
| SCHEMBL8675092 | 0.72 | ALDH1A1 (0.56) | ALDH1A1NT5ELMNAKDM4EPOLB | |
| SCHEMBL1555373 | 0.71 | ALDH1A1 (0.50) | CDK2ALDH1A1ATAD2NT5ELMNA | |
| SCHEMBL10107868 | 0.70 | KDM4E (0.49) | ALDH1A1ATAD2NT5ELMNAKDM4E | |
| SCHEMBL13314195 | 0.70 | ALDH1A1 (0.49) | ALDH1A1ATAD2NT5ELMNADPYD | |
| SCHEMBL6111238 | 0.69 | ALDH1A1 (0.43) | ALDH1A1ATAD2NT5ELMNADPYD | |
| SCHEMBL13314288 | 0.69 | ALDH1A1 (0.43) | ALDH1A1ATAD2NT5ELMNAROCK1 | |
| Hydrochloric Acid SCHEMBL2745406 | 0.69 | KDM4E (0.48) | ALDH1A1ATAD2NT5ELMNAKDM4E | |
| Hydrochloric Acid SCHEMBL3558338 | 0.69 | ALDH1A1 (0.47) | ALDH1A1ATAD2NT5ELMNADPYD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547657-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119384415-A | CD73 compounds | 吉利德科学公司 | 2025-01-28 | — | — | CN | disclosed |
| WO-2024006929-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-01-04 | — | — | WO | disclosed |