Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3697656 | 0.92 | TSHR (0.39) | CYP3A4TSHRCYP2C19CHRNB2CHRNB4 | |
| SCHEMBL16669575 | 0.89 | CHRM3 (0.42) | CYP3A4TSHRCYP2C19CHRNB2CHRNB4 | |
| SCHEMBL28181705 | 0.88 | CHRM3 (0.34) | CYP3A4TSHRCYP2C19ITGAVITGB6 | |
| SCHEMBL12206756 | 0.85 | CHRNB2 (0.44) | CYP3A4TSHRCYP2C19CHRNB2CHRNB4 | |
| SCHEMBL22679987 | 0.80 | CHRM1 (0.38) | CHRNB2CHRNA7CHRNA4EPHX1CHRM3 | |
| SCHEMBL22679959 | 0.80 | CHRM1 (0.38) | CHRNB2CHRNA7CHRNA4EPHX1CHRM3 | |
| SCHEMBL22680122 | 0.80 | CHRM1 (0.38) | CHRNB2CHRNA7CHRNA4EPHX1CHRM3 | |
| SCHEMBL14501550 | 0.79 | EPHX1 (0.47) | CYP3A4TSHRCYP2C19CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL22655478 | 0.79 | CHRM1 (0.37) | EPHX1CHRM3 | |
| Hydrochloric Acid SCHEMBL22655453 | 0.79 | CHRM1 (0.37) | EPHX1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547657-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006929-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-01-04 | — | — | WO | disclosed |