Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | DDO | Q99489 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22186888 | 1.00 | HDAC1 (0.42) | HDAC1CYP11B1CYP11B2ALDH1A1KDM4E | |
| SCHEMBL24952236 | 0.83 | CYP11B1 (0.51) | CYP11B1CYP11B2ALDH1A1KDM4ELMNA | |
| SCHEMBL30202942 | 0.83 | CYP11B1 (0.51) | CYP11B1CYP11B2ALDH1A1KDM4ELMNA | |
| SCHEMBL1532963 | 0.82 | HSP90AB1 (0.47) | HDAC1CYP11B1CYP11B2ALDH1A1KDM4E | |
| SCHEMBL3931688 | 0.81 | CYP11B1 (0.48) | CYP11B1CYP11B2ALDH1A1KDM4ELMNA | |
| SCHEMBL21476653 | 0.81 | CYP11B1 (0.41) | HDAC1CYP11B1CYP11B2ALDH1A1KDM4E | |
| SCHEMBL751036 | 0.81 | CYP11B1 (0.48) | CYP11B1CYP11B2KDM4EKMT2ATBXAS1 | |
| SCHEMBL22364153 | 0.80 | HDAC1 (0.45) | HDAC1CYP11B1CYP11B2SIRT2CCNC | |
| SCHEMBL21475991 | 0.78 | CYP11B1 (0.39) | HDAC1CYP11B1CYP11B2ALDH1A1KDM4E | |
| SCHEMBL7013456 | 0.78 | CYP11B1 (0.46) | HDAC1CYP11B1CYP11B2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565574-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |