Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | ERN1 | O75460 | 3/20 | 0.36 |
| ▸ | PTGES | O14684 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.35 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191924 | 1.00 | KDM4E (0.41) | KDM4EHTTNPEPPSGAATP53 | |
| SCHEMBL27192346 | 0.92 | KDM4E (0.46) | KDM4EHTTNPEPPSGAATP53 | |
| SCHEMBL27191798 | 0.88 | KDM4E (0.43) | KDM4EHTTNPEPPSGAATP53 | |
| SCHEMBL27191759 | 0.87 | PTGES (0.46) | KDM4EHTTNPEPPSGAATP53 | |
| SCHEMBL27192074 | 0.87 | KDM4E (0.42) | KDM4EHTTNPEPPSGAATP53 | |
| SCHEMBL27378574 | 0.86 | KDM4E (0.41) | KDM4EHTTNPEPPSGAATP53 | |
| SCHEMBL27191898 | 0.85 | KDM4E (0.41) | KDM4EHTTNPEPPSGAATP53 | |
| SCHEMBL27378403 | 0.85 | TP53 (0.41) | KDM4EHTTNPEPPSGAATP53 | |
| SCHEMBL27377882 | 0.85 | GRIA1 (0.48) | KDM4EHTTNPEPPSGAATP53 | |
| SCHEMBL27378401 | 0.85 | GRIA1 (0.48) | KDM4EHTTNPEPPSGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565574-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-11 | — | — | EP | disclosed |
| CN-119731159-A | SARS-CoV2 main proteinase inhibitor | 吉利德科学公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |