Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27192321 | 1.00 | HSD17B10 (0.43) | HSD17B10PKMCYP11B1CYP11B2TUBB4A | |
| SCHEMBL27381609 | 0.93 | CYP11B1 (0.41) | HSD17B10PKMCYP11B1CYP11B2CLK1 | |
| SCHEMBL27380555 | 0.91 | HSD17B10 (0.48) | HSD17B10PKMCYP11B1CYP11B2TUBB4A | |
| SCHEMBL27191737 | 0.89 | KDM4E (0.39) | HSD17B10PKMCYP11B1CYP11B2CLK1 | |
| SCHEMBL30701974 | 0.89 | KDM4E (0.39) | HSD17B10PKMCYP11B1CYP11B2CLK1 | |
| SCHEMBL27379524 | 0.88 | HSD17B10 (0.45) | HSD17B10PKMCYP11B1CYP11B2TUBB4A | |
| SCHEMBL27378015 | 0.88 | CYP11B1 (0.44) | CYP11B1CYP11B2CDK5DYRK1ACDK5R1 | |
| SCHEMBL27191736 | 0.86 | HSD17B10 (0.47) | HSD17B10PKMCYP11B1CYP11B2TUBB4A | |
| SCHEMBL27381710 | 0.85 | CLK1 (0.39) | HSD17B10CYP11B1CYP11B2CLK1CYP1A2 | |
| SCHEMBL30702073 | 0.84 | ALDH1A1 (0.41) | HSD17B10PKMCYP11B1CYP11B2CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565574-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-11 | — | — | EP | disclosed |
| CN-119731159-A | SARS-CoV2 main proteinase inhibitor | 吉利德科学公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |