Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 5/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20359750 | 1.00 | NPC1 (0.40) | NPC1RAB9AMAPTALDH1A1PKM | |
| SCHEMBL20360230 | 0.77 | NPC1 (0.36) | NPC1RAB9AMAPTALDH1A1PKM | |
| SCHEMBL30702173 | 0.77 | NPC1 (0.36) | NPC1RAB9AMAPTALDH1A1PKM | |
| SCHEMBL20360369 | 0.74 | NOTUM (0.65) | NPC1RAB9AMAPTALDH1A1POLB | |
| SCHEMBL30702126 | 0.74 | NOTUM (0.65) | NPC1RAB9AMAPTALDH1A1POLB | |
| SCHEMBL20360173 | 0.74 | NPC1 (0.36) | NPC1RAB9AMAPTALDH1A1PKM | |
| SCHEMBL30702174 | 0.74 | NPC1 (0.36) | NPC1RAB9AMAPTALDH1A1PKM | |
| SCHEMBL20359774 | 0.70 | PLCG2 (0.39) | NPC1RAB9AMAPTPKMALOX15 | |
| SCHEMBL30702169 | 0.70 | PLCG2 (0.39) | NPC1RAB9AMAPTPKMALOX15 | |
| SCHEMBL20599056 | 0.69 | S100A4 (0.46) | ALDH1A1ALOX15SMN1; SMN2HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292539-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2023-12-22 | — | — | CN | disclosed |