Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.39 |
| ▸ | JAK2 | O60674 | 5/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25897580 | 0.86 | TYK2 (0.43) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL30703074 | 0.86 | TYK2 (0.34) | TYK2JAK2 | |
| SCHEMBL30663452 | 0.82 | TYK2 (0.37) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL25897582 | 0.82 | TYK2 (0.61) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL30703091 | 0.81 | TYK2 (0.39) | TYK2JAK2JAK1 | |
| SCHEMBL29766555 | 0.80 | TYK2 (0.45) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL25314251 | 0.79 | TYK2 (0.54) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL25316583 | 0.79 | TYK2 (0.49) | TYK2JAK2JAK1STAT3 | |
| SCHEMBL29766381 | 0.79 | TYK2 (0.49) | TYK2JAK2JAK1STAT3 | |
| SCHEMBL25897719 | 0.78 | JAK1 (0.44) | TYK2JAK1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377669-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-117377669-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2024-01-09 | — | — | CN | disclosed |