Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.37 |
| ▸ | JAK2 | O60674 | 4/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30703087 | 0.94 | TYK2 (0.39) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL30703084 | 0.90 | TYK2 (0.38) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL30703094 | 0.90 | TYK2 (0.40) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL30663463 | 0.86 | TYK2 (0.38) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL30703096 | 0.84 | TYK2 (0.37) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL30703073 | 0.83 | NUDT1 (0.43) | TYK2JAK1STAT3 | |
| SCHEMBL25897794 | 0.83 | TYK2 (0.51) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL30703069 | 0.82 | TYK2 (0.39) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL29766494 | 0.82 | TYK2 (0.59) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL25897194 | 0.82 | TYK2 (0.59) | TYK2JAK2JAK1STAT3JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120440-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-117377669-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117120440-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-11-24 | — | — | CN | disclosed |