Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5617167 | 0.85 | POLB (0.45) | MAOBPOLBHPGDTYRDAO | |
| SCHEMBL7522059 | 0.85 | KDM4E (0.52) | MAOBMAOAPOLBHPGDTYR | |
| SCHEMBL14634607 | 0.84 | HPGD (0.47) | MAOBPOLBHPGDTYRDAO | |
| SCHEMBL38651911 | 0.84 | MAOB (0.53) | MAOBMAOAPOLBHPGDTYR | |
| SCHEMBL11098991 | 0.84 | ALDH1A1 (0.53) | MAOBMAOAPOLBHPGDTYR | |
| SCHEMBL11303840 | 0.84 | POLB (0.50) | MAOBPOLBHPGDTYRDAO | |
| SCHEMBL7566904 | 0.82 | KDM4E (0.58) | MAOBMAOAPOLBHPGDTYR | |
| SCHEMBL28816255 | 0.82 | ALDH1A1 (0.53) | MAOBPOLBHPGDTYRDAO | |
| SCHEMBL15635414 | 0.81 | POLB (0.49) | MAOBMAOAPOLBHPGDTYR | |
| Hydrochloric Acid SCHEMBL31460606 | 0.81 | POLB (0.50) | MAOBPOLBHPGDTYRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |