SCHEMBL30705204

SCHEMBL30705204

CCCCc1cccnc1.F[B-](F)(F)F

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.77
L3MBTL1 Q9Y468 1/20 0.77
CYP2A6 P11509 1/20 0.58
HRH1 P35367 2/20 0.54
CHRNA7 P36544 2/20 0.52
TBXAS1 P24557 4/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HRH4 Q9H3N8 1/20 0.49
HRH3 Q9Y5N1 1/20 0.49
TRPV1 Q8NER1 1/20 0.48
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
CASP3 P42574 1/20 0.48
RAB9A P51151 1/20 0.48
KMT2A Q03164 1/20 0.48
SENP8 Q96LD8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28153899 0.95 TDP1 (0.86) TDP1L3MBTL1CYP2A6HRH1CHRNA7
SCHEMBL681571 0.93 TDP1 (0.89) TDP1L3MBTL1CYP2A6HRH1CHRNA7
SCHEMBL28193002 0.91 TDP1 (0.85) TDP1L3MBTL1CYP2A6HRH1CHRNA7
Fluoride SCHEMBL29204969 0.91 TDP1 (0.85) TDP1L3MBTL1CYP2A6HRH1CHRNA7
Hydrochloric Acid SCHEMBL29205003 0.91 TDP1 (0.85) TDP1L3MBTL1CYP2A6HRH1CHRNA7
SCHEMBL18301254 0.91 TDP1 (0.85) TDP1L3MBTL1CYP2A6HRH1CHRNA7
Bromide SCHEMBL28337045 0.91 TDP1 (0.85) TDP1L3MBTL1CYP2A6HRH1CHRNA7
Dimethylamine SCHEMBL7749424 0.87 TDP1 (0.79) TDP1L3MBTL1CYP2A6HRH1CHRNA7
SCHEMBL135032 0.87 TDP1 (1.00) TDP1L3MBTL1CYP2A6HRH1CHRNA7
SCHEMBL25380936 0.85 TDP1 (0.96) TDP1L3MBTL1CYP2A6HRH1CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117361808-A Method and system for removing inert organic matters in high-salt wastewater in coal chemical industry 北京中力信达环境技术有限公司 2024-01-09 CN disclosed