SCHEMBL30705372

SCHEMBL30705372

NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 1/20 0.57
CPB2 Q96IY4 1/20 0.57
SIRT2 Q8IXJ6 3/20 0.56
SIRT1 Q96EB6 3/20 0.56
SIRT3 Q9NTG7 2/20 0.56
ECE1 P42892 2/20 0.55
ACE P12821 1/20 0.55
MME P08473 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TLR2 O60603 2/20 0.52
FOLH1 Q04609 2/20 0.52
ITGB3 P05106 4/20 0.50
ITGA2B P08514 4/20 0.50
CTSL P07711 1/20 0.50
CTSS P25774 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30064582 0.87 ECE1 (0.64) CPB1CPB2SIRT2SIRT1SIRT3
SCHEMBL4182645 0.86 CPB1 (0.62) CPB1CPB2SIRT2SIRT1SIRT3
SCHEMBL12109902 0.85 SMN1; SMN2 (0.54) ECE1MMESMN1; SMN2CTSLCTSS
SCHEMBL29171059 0.85 FOLH1 (0.56) ECE1MMESMN1; SMN2FOLH1
SCHEMBL9319378 0.85 FOLH1 (0.56) ECE1MMESMN1; SMN2FOLH1
SCHEMBL12109819 0.84 SMN1; SMN2 (0.55) ECE1MMESMN1; SMN2ITGB3ITGA2B
SCHEMBL12265769 0.84 SMN1; SMN2 (0.55) ECE1MMESMN1; SMN2ITGB3ITGA2B
SCHEMBL30914622 0.84 SMN1; SMN2 (0.58) ECE1MMESMN1; SMN2CTSLCTSS
SCHEMBL9516479 0.84 SIRT2 (0.62) CPB1CPB2SIRT2SIRT1SIRT3
SCHEMBL29437121 0.84 SMN1; SMN2 (0.62) ECE1MMESMN1; SMN2CTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250376518-A1 Anti-mGluR2 Biparatopic Nanobodies and Uses Thereof UNIVERSITE DE MONTPELLIER (FR) 2025-12-11 US disclosed
EP-4547332-A1 ANTI-MGLUR2 BIPARATOPIC NANOBODIES AND USES THEREOF UNIVERSITE DE MONTPELLIER (FR) 2025-05-07 EP disclosed
WO-2024003390-A1 ANTI-MGLUR2 NANOBODIES FOR USE AS BIOMOLECULE TRANSPORTER UNIVERSITE DE MONTPELLIER (FR) 2024-01-04 WO disclosed
WO-2024003389-A1 ANTI-MGLUR2 BIPARATOPIC NANOBODIES AND USES THEREOF UNIVERSITE DE MONTPELLIER (FR) 2024-01-04 WO disclosed
EP-4299125-A1 ANTI-MGLUR2 BIPARATOPIC NANOBODIES AND USES THEREOF UNIVERSITE DE MONTPELLIER (FR) 2024-01-03 EP disclosed
EP-4299124-A1 ANTI-MGLUR2 NANOBODIES FOR USE AS BIOMOLECULE TRANSPORTER UNIVERSITE DE MONTPELLIER (FR) 2024-01-03 EP disclosed