SCHEMBL30705406

SCHEMBL30705406

CN1CCCC(Cc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2)C1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 0.79
PTPN2 P17706 18/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30705414 0.97 PTPN1 (0.81) PTPN1PTPN2
SCHEMBL30705409 0.94 PTPN1 (0.76) PTPN1PTPN2
SCHEMBL12009128 0.90 PTPN1 (0.94) PTPN1PTPN2
SCHEMBL12009130 0.90 PTPN1 (0.98) PTPN1PTPN2
Potassium SCHEMBL2889366 0.89 PTPN1 (0.92) PTPN1PTPN2
SCHEMBL2896988 0.89 PTPN1 (1.00) PTPN1PTPN2
SCHEMBL2889362 0.89 PTPN1 (0.92) PTPN1PTPN2
SCHEMBL30705407 0.84 PTPN2 (0.73) PTPN1PTPN2
SCHEMBL30705410 0.83 PTPN1 (0.78) PTPN1PTPN2
SCHEMBL25327208 0.82 PTPN1 (0.58) PTPN1PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4508050-A1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND USES THEREOF Nerio Therapeutics, Inc. (US) 2025-02-19 EP disclosed
CN-119365452-A Protein tyrosine phosphatase inhibitors and uses thereof 耐瑞欧医疗公司 2025-01-24 CN disclosed
WO-2023200964-A1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND USES THEREOF NERIO THERAPEUTICS, INC. (US) 2023-10-19 WO disclosed