SCHEMBL30705407

SCHEMBL30705407

CN1CCC(CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2)C1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 18/20 0.73
PTPN1 P18031 6/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30705409 0.90 PTPN1 (0.76) PTPN2PTPN1
SCHEMBL30705406 0.84 PTPN1 (0.79) PTPN2PTPN1
SCHEMBL26509436 0.84 PTPN1 (0.61) PTPN2PTPN1
SCHEMBL30705414 0.83 PTPN1 (0.81) PTPN2PTPN1
SCHEMBL25325685 0.83 PTPN2 (0.61) PTPN2PTPN1
SCHEMBL26509457 0.82 PTPN1 (0.59) PTPN2PTPN1
SCHEMBL31758184 0.81 PTPN1 (0.67) PTPN2PTPN1
SCHEMBL30705415 0.80 PTPN2 (0.71) PTPN2PTPN1
SCHEMBL12009129 0.79 PTPN1 (0.68) PTPN2PTPN1
SCHEMBL30705413 0.79 PTPN2 (0.69) PTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4508050-A1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND USES THEREOF Nerio Therapeutics, Inc. (US) 2025-02-19 EP disclosed
CN-119365452-A Protein tyrosine phosphatase inhibitors and uses thereof 耐瑞欧医疗公司 2025-01-24 CN disclosed
WO-2023200964-A1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND USES THEREOF NERIO THERAPEUTICS, INC. (US) 2023-10-19 WO disclosed