SCHEMBL30705455

SCHEMBL30705455

NC(=O)C(N)Cc1cc2c([nH]c1=O)CCOC2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30705688 0.81 KDM4E (0.49) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL32662205 0.78 GRIA1 (0.37) KDM4EALDH1A1HPGDHSD17B10
Hydrochloric Acid SCHEMBL30705654 0.75
Hydrochloric Acid SCHEMBL30705545 0.75
SCHEMBL31376407 0.74 KDM4E (0.46) KDM4EALDH1A1HPGDHSD17B10HTT
SCHEMBL20939569 0.70 KDM4E (0.33) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL17678623 0.70 KDM4E (0.64) KDM4EALDH1A1HPGDHSD17B10HTT
SCHEMBL24159176 0.69 MAP2K1 (0.37) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL20939530 0.68 TNKS2 (0.38) KDM4EALDH1A1HPGDHSD17B10HTT
SCHEMBL32662518 0.66 KDM4E (0.39) KDM4EALDH1A1HPGDHSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4539844-A2 COMPOUNDS FOR TREATMENT OF A CORONAVIRUS INFECTION Trawsfynydd Therapeutics, Inc. (US) 2025-04-23 EP disclosed
CN-119604290-A Compounds for the treatment of coronavirus infections 特劳斯芬尼德治疗股份有限公司 2025-03-11 CN disclosed
WO-2023245166-A2 COMPOUNDS FOR TREATMENT OF A CORONAVIRUS INFECTION TRAWSFYNYDD THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed